Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death

Atypically expressed transglutaminase 2 (TG2) has been identified as a poor prognostic factor in a variety of cancers. In this study, we evaluated the contribution of TG2 to the prolonged cell survival of differentiated acute promyelocytic leukaemia (APL) cells in response to the standard treatment...

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Detalles Bibliográficos
Autores principales: Jambrovics, Károly, Botó, Pál, Pap, Attila, Sarang, Zsolt, Kolostyák, Zsuzsanna, Czimmerer, Zsolt, Szatmari, Istvan, Fésüs, László, Uray, Iván P., Balajthy, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050012/
https://www.ncbi.nlm.nih.gov/pubmed/36977701
http://dx.doi.org/10.1038/s41419-023-05748-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050012/
https://www.ncbi.nlm.nih.gov/pubmed/36977701
http://dx.doi.org/10.1038/s41419-023-05748-6

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