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Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death
Atypically expressed transglutaminase 2 (TG2) has been identified as a poor prognostic factor in a variety of cancers. In this study, we evaluated the contribution of TG2 to the prolonged cell survival of differentiated acute promyelocytic leukaemia (APL) cells in response to the standard treatment...
Autores principales: | Jambrovics, Károly, Botó, Pál, Pap, Attila, Sarang, Zsolt, Kolostyák, Zsuzsanna, Czimmerer, Zsolt, Szatmari, Istvan, Fésüs, László, Uray, Iván P., Balajthy, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050012/ https://www.ncbi.nlm.nih.gov/pubmed/36977701 http://dx.doi.org/10.1038/s41419-023-05748-6 |
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