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Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity

Studying the interplay between genetic variation, epigenetic changes, and regulation of gene expression is crucial to understand the modification of cellular states in various conditions, including immune diseases. In this study, we characterize the cell-specificity in three key cells of the human i...

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Detalles Bibliográficos
Autores principales: Avalos, Diana, Rey, Guillaume, Ribeiro, Diogo M., Ramisch, Anna, Dermitzakis, Emmanouil T., Delaneau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050075/
https://www.ncbi.nlm.nih.gov/pubmed/36977773
http://dx.doi.org/10.1038/s42003-023-04688-3