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Norepinephrine inhibits CD8(+) T-cell infiltration and function, inducing anti-PD-1 mAb resistance in lung adenocarcinoma
BACKGROUND: Mental stress-induced neurotransmitters can affect the immune system in various ways. Therefore, a better understanding of the role of neurotransmitters in the tumour immune microenvironment is expected to promote the development of novel anti-tumour therapies. METHODS: In this study, we...
Autores principales: | Geng, Qishun, Li, Lifeng, Shen, Zhibo, Zheng, Yuanyuan, Wang, Longhao, Xue, Ruyue, Xue, Wenhua, Peng, Mengle, Zhao, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050078/ https://www.ncbi.nlm.nih.gov/pubmed/36646807 http://dx.doi.org/10.1038/s41416-022-02132-7 |
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