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Susceptibility of SARS COV-2 nucleocapsid and spike proteins to reactive oxygen species and role in inflammation
Chemiluminescence was used to test the susceptibility of the SARS-CoV-2 N and S proteins to oxidation by reactive oxygen species (ROS) at pH 7.4 and pH 8.5. The Fenton's system generates various ROS (H(2)O(2), (•)OH, (–)OH, (•)OOH). All proteins were found to significantly suppress oxidation (t...
Autores principales: | Pavlova, Elitsa, Genova-Kalou, Petya, Dyankov, Georgi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050197/ https://www.ncbi.nlm.nih.gov/pubmed/36997015 http://dx.doi.org/10.1016/j.ab.2023.115137 |
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