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TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

Retinal detachment (RD) occurs in several major retinal conditions and often causes irreversible vision loss due to photoreceptor cell death. Retinal residential microglial cells are activated following RD and participate in photoreceptor cell death via direct phagocytosis and the regulation of infl...

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Detalles Bibliográficos
Autores principales: Zhou, Wenchuan, Zhou, Yutong, He, Jincan, Rao, Yuqing, Fei, Ping, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050330/
https://www.ncbi.nlm.nih.gov/pubmed/36977680
http://dx.doi.org/10.1038/s41419-023-05735-x