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Population PK/PD modelling of meropenem in preterm newborns based on therapeutic drug monitoring data

Background: Preterm neonates rarely participate in clinical trials, this leads to lack of adequate information on pharmacokinetics for most drugs in this population. Meropenem is used in neonates to treat severe infections, and absence of evidence-based rationale for optimal dosing could result in m...

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Detalles Bibliográficos
Autores principales: Zyryanov, Sergey, Bondareva, Irina, Butranova, Olga, Kazanova, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050386/
https://www.ncbi.nlm.nih.gov/pubmed/37007022
http://dx.doi.org/10.3389/fphar.2023.1079680