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Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility

BACKGROUND: Oestrogen receptor (ER) signalling-dependent cancer cell growth is one of the major features of ER-positive breast cancer (BC). Inhibition of ER function is a standard and effective treatment for ER-positive tumours; however, ~20% of patients with ER-positive BC experience early or late...

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Detalles Bibliográficos
Autores principales: Kumegawa, Kohei, Saeki, Sumito, Takahashi, Yoko, Yang, Liying, Osako, Tomo, Nakadai, Tomoyoshi, Amino, Sayuri, Maeda, Tetsuyo, Takahata, Chikako, Mori, Seiichi, Noda, Tetsuo, Ohno, Shinji, Ueno, Takayuki, Maruyama, Reo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050410/
https://www.ncbi.nlm.nih.gov/pubmed/36725920
http://dx.doi.org/10.1038/s41416-023-02178-1