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Syk inhibitors protect against microglia-mediated neuronal loss in culture
Microglia are brain macrophages and play beneficial and/or detrimental roles in many brain pathologies because of their inflammatory and phagocytic activity. Microglial inflammation and phagocytosis are thought to be regulated by spleen tyrosine kinase (Syk), which is activated by multiple microglia...
Autores principales: | Birkle, Timothy J. Y., Brown, Guy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050448/ https://www.ncbi.nlm.nih.gov/pubmed/37009452 http://dx.doi.org/10.3389/fnagi.2023.1120952 |
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