T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing

BACKGROUND: Hepatocellular carcinoma (HCC), the third most prevalent cause of cancer-related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T-cell depletion (TEX) is a progressive decline in T-cell function due to continuous stimulation of the TCR in the prese...

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Detalles Bibliográficos
Autores principales: Chi, Hao, Zhao, Songyun, Yang, Jinyan, Gao, Xinrui, Peng, Gaoge, Zhang, Jinhao, Xie, Xixi, Song, Guobin, Xu, Ke, Xia, Zhijia, Chen, Shi, Zhao, Jinqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050519/
https://www.ncbi.nlm.nih.gov/pubmed/37006257
http://dx.doi.org/10.3389/fimmu.2023.1137025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050519/
https://www.ncbi.nlm.nih.gov/pubmed/37006257
http://dx.doi.org/10.3389/fimmu.2023.1137025

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