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Factors affecting the role of canonical Wnt inhibitor Dickkopf-1 in cancer progression

BACKGROUND: The canonical Wnt inhibitor Dickkopf-1 (Dkk-1) has the capacity to modulate homeostasis between canonical and non-canonical Wnt pathways and also signal independently of Wnt. The specific effects of Dkk-1 activity on tumor physiology are therefore unpredictable with examples of Dkk-1 ser...

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Detalles Bibliográficos
Autores principales: Doucet, Dakota, Brubaker, Connor, Turner, Donald, Gregory, Carl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050559/
https://www.ncbi.nlm.nih.gov/pubmed/37007131
http://dx.doi.org/10.3389/fonc.2023.1114822