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Investigating the effect of dehydromiltirone on septic AKI using a network pharmacology method, molecular docking, and experimental validation
Acute kidney injury (AKI) is a severe and frequent complication of sepsis that occurs in intensive care units with inflammation and rapid decline in renal function as the main pathological features. Systemic inflammation, microvascular dysfunction, and tubule injury are the main causes of sepsis-ind...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050741/ https://www.ncbi.nlm.nih.gov/pubmed/37007048 http://dx.doi.org/10.3389/fphar.2023.1145675 |