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Humoral immune responses remain quantitatively impaired but improve qualitatively in anti-CD20-treated patients with multiple sclerosis after three or four COVID-19 vaccinations

OBJECTIVE: To analyze anti-SARS-CoV-2-S1-IgG levels, avidity, Omicron BA.2 variant neutralizing capacity, and SARS-CoV-2-specific T cells in anti-CD20-treated patients with multiple sclerosis (aCD20pwMS) after two, three, or four COVID-19 vaccinations. RESULTS: Frequencies of aCD20pwMS with detectab...

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Detalles Bibliográficos
Autores principales: Otto, Carolin, Schwarz, Tatjana, Jeworowski, Lara M, Schmidt, Marie L, Walper, Felix, Pache, Florence, Schindler, Patrick, Niederschweiberer, Moritz, Krumbholz, Andi, Rose, Ruben, Drosten, Christian, Ruprecht, Klemens, Corman, Victor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051002/
https://www.ncbi.nlm.nih.gov/pubmed/36974938
http://dx.doi.org/10.1177/13524585231161253