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Prevalence of Neutralizing Antibodies against Adeno-Associated Virus Serotypes 1, 2, and 9 in Non-Injected Latin American Patients with Heart Failure—ANVIAS Study

Neutralizing antibody (NAb) activity against the viral capsid of adeno-associated viral (AAV) vectors decreases transduction efficiency, thus limiting transgene expression. Several reports have mentioned a variation in NAb prevalence according to age, AAV serotype, and, most importantly, geographic...

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Detalles Bibliográficos
Autores principales: Sierra-Delgado, Julieth A., Likhite, Shibi, Bautista, Paula K., Gómez-Ochoa, Sergio A., Echeverría, Luis E., Guío, Elizabeth, Vargas, Clara, Serrano, Norma C., Meyer, Kathrin C., Rincon, Melvin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051173/
https://www.ncbi.nlm.nih.gov/pubmed/36982654
http://dx.doi.org/10.3390/ijms24065579