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Prevalence of Neutralizing Antibodies against Adeno-Associated Virus Serotypes 1, 2, and 9 in Non-Injected Latin American Patients with Heart Failure—ANVIAS Study
Neutralizing antibody (NAb) activity against the viral capsid of adeno-associated viral (AAV) vectors decreases transduction efficiency, thus limiting transgene expression. Several reports have mentioned a variation in NAb prevalence according to age, AAV serotype, and, most importantly, geographic...
Autores principales: | Sierra-Delgado, Julieth A., Likhite, Shibi, Bautista, Paula K., Gómez-Ochoa, Sergio A., Echeverría, Luis E., Guío, Elizabeth, Vargas, Clara, Serrano, Norma C., Meyer, Kathrin C., Rincon, Melvin Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051173/ https://www.ncbi.nlm.nih.gov/pubmed/36982654 http://dx.doi.org/10.3390/ijms24065579 |
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