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Comparing the Effects of Rocaglates on Energy Metabolism and Immune Modulation on Cells of the Human Immune System

A promising new approach to broad spectrum antiviral drugs is the inhibition of the eukaryotic translation initiation factor 4A (elF4A), a DEAD-box RNA helicase that effectively reduces the replication of several pathogenic virus types. Beside the antipathogenic effect, modulation of a host enzyme a...

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Detalles Bibliográficos
Autores principales: Schiffmann, Susanne, Henke, Marina, Seifert, Michelle, Ulshöfer, Thomas, Roser, Luise A., Magari, Francesca, Wendel, Hans-Guido, Grünweller, Arnold, Parnham, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051175/
https://www.ncbi.nlm.nih.gov/pubmed/36982945
http://dx.doi.org/10.3390/ijms24065872