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SPECT Imaging with Tc-99m-Labeled HYNIC-FAPI-04 to Extend the Differential Time Window in Evaluating Tumor Fibrosis

The so-far used Ga-68- or F-18-labelled tracers are of a relative short time window in differentiating tumor fibrosis. SPECT applicable imaging probe, (99m)Tc-HYNIC-FAPI-04, was synthesized and evaluated in tumor cells and animal models of FAP-positive glioma and FAP-negative hepatoma, and then comp...

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Detalles Bibliográficos
Autores principales: Luo, Xiu, Zhang, Zhe, Cheng, Chao, Wang, Tao, Fang, Danzhou, Zuo, Changjing, Yuan, Gengbiao, Li, Rou, Li, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051245/
https://www.ncbi.nlm.nih.gov/pubmed/36986521
http://dx.doi.org/10.3390/ph16030423