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A Retrospective Study of the Efficacy and Safety of Naldemedine for Treatment of Opioid-Induced Constipation in Patients with Hepatobiliary Pancreatic Cancer

Background and Objectives: Opioid analgesics, which are used for cancer-related pain management, cause opioid-induced constipation (OIC). Naldemedine, a peripheral opioid receptor antagonist, is an OIC-modifying agent, but no focused efficacy and safety analysis has been conducted for its use in hep...

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Detalles Bibliográficos
Autores principales: Kamiya, Teruhiko, Imai, Hisao, Fujita, Yukiyoshi, Hiruta, Eriko, Masuno, Takashi, Yamazaki, Shigeki, Tanaka, Hajime, Sandoh, Mitsuru, Takei, Satoshi, Arai, Kazuya, Nishiba, Hiromi, Mogi, Junnosuke, Koizuka, Shiro, Saito, Taeko, Obayashi, Kyoko, Kaira, Kyoichi, Minato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051263/
https://www.ncbi.nlm.nih.gov/pubmed/36984494
http://dx.doi.org/10.3390/medicina59030492