An X-Domain Phosphoinositide Phospholipase C (PI-PLC-like) of Trypanosoma brucei Has a Surface Localization and Is Essential for Proliferation

Trypanosoma brucei is the causative agent of African trypanosomiasis, a deadly disease that affects humans and cattle. There are very few drugs to treat it, and there is evidence of mounting resistance, raising the need for new drug development. Here, we report the presence of a phosphoinositide pho...

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Detalles Bibliográficos
Autores principales: Negrão, Núria W., Crowe, Logan P., Mantilla, Brian S., Baptista, Rodrigo P., King-Keller, Sharon, Huang, Guozhong, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051276/
https://www.ncbi.nlm.nih.gov/pubmed/36986308
http://dx.doi.org/10.3390/pathogens12030386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051276/
https://www.ncbi.nlm.nih.gov/pubmed/36986308
http://dx.doi.org/10.3390/pathogens12030386

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