Cargando…
Neoprzewaquinone A Inhibits Breast Cancer Cell Migration and Promotes Smooth Muscle Relaxation by Targeting PIM1 to Block ROCK2/STAT3 Pathway
Salvia miltiorrhiza Bunge (Danshen) has been widely used to treat cancer and cardiovascular diseases in Chinese traditional medicine. Here, we found that Neoprzewaquinone A (NEO), an active component of S. miltiorrhiza, selectively inhibits PIM1. We showed that NEO potently inhibits PIM1 kinase at n...
Autores principales: | Zhao, Guiying, Ren, Yali, Yan, Jie, Zhang, Tingrui, Lu, Peng, Lei, Jieting, Rao, Huanan, Kang, Xin, Cao, Zhixing, Peng, Fu, Peng, Cheng, Rao, Chaolong, Li, Yuzhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051292/ https://www.ncbi.nlm.nih.gov/pubmed/36982538 http://dx.doi.org/10.3390/ijms24065464 |
Ejemplares similares
-
Ibrutinib Prevents Acute Lung Injury via Multi-Targeting BTK, FLT3 and EGFR in Mice
por: Rao, Huanan, et al.
Publicado: (2022) -
Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism
por: Absi, Mais, et al.
Publicado: (2019) -
Rock blocks
por: Turner, W
Publicado: (2009) -
Dandelion extract relaxes mouse airway smooth muscle by blocking VDLCC and NSCC channels
por: Zhao, Ping, et al.
Publicado: (2020) -
Cortex phellodendri Extract Relaxes Airway Smooth Muscle
por: Jiang, Qiu-Ju, et al.
Publicado: (2016)