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IL-27 Signaling Promotes Th1 Response by Downregulating IL-10 Production in DCs during Chlamydial Respiratory Infection

Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response and suppressing neutrophilic inflammation. Here...

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Detalles Bibliográficos
Autores principales: Zeng, Jiajia, Yang, Shuaini, Tuo, Yuqing, Zha, Xiaoyu, Sun, Ruoyuan, Lu, Tingsha, Zhang, Hong, Tan, Lu, Qiao, Sai, Bai, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051384/
https://www.ncbi.nlm.nih.gov/pubmed/36985179
http://dx.doi.org/10.3390/microorganisms11030604