Cargando…

IL-27 Signaling Promotes Th1 Response by Downregulating IL-10 Production in DCs during Chlamydial Respiratory Infection

Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response and suppressing neutrophilic inflammation. Here...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Jiajia, Yang, Shuaini, Tuo, Yuqing, Zha, Xiaoyu, Sun, Ruoyuan, Lu, Tingsha, Zhang, Hong, Tan, Lu, Qiao, Sai, Bai, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051384/ https://www.ncbi.nlm.nih.gov/pubmed/36985179 http://dx.doi.org/10.3390/microorganisms11030604

Ejemplares similares

IL-21/IL-21R Regulates the Neutrophil-Mediated Pathologic Immune Response during Chlamydial Respiratory Infection
por: Zeng, Jiajia, et al.
Publicado: (2022)

A Pathogenic Role for FcγRI in the Immune Response against Chlamydial Respiratory Infection
por: Zeng, Jiajia, et al.
Publicado: (2022)

IL-21/IL-21R Promotes the Pro-Inflammatory Effects of Macrophages during C. muridarum Respiratory Infection
por: Yang, Shuaini, et al.
Publicado: (2023)

In Silico Identification and Validation of Pyroptosis-Related Genes in Chlamydia Respiratory Infection
por: Sun, Ruoyuan, et al.
Publicado: (2023)

Vγ4+ T Cells: A Novel IL-17-Producing γδ T Subsets during the Early Phase of Chlamydial Airway Infection in Mice
por: Sun, Li-da, et al.
Publicado: (2018)

Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis
por: von Glehn, Felipe, et al.
Publicado: (2023)

Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes
por: Tang, Hui, et al.
Publicado: (2016)

Associations of IL-27 Polymorphisms and Serum IL-27p28 Levels With Osteosarcoma Risk
por: Tang, Yu-jin, et al.
Publicado: (2014)

IL-17A Synergizes with IFN-γ to Upregulate iNOS and NO Production and Inhibit Chlamydial Growth
por: Zhang, Yongci, et al.
Publicado: (2012)

Erratum: Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes
por: Tang, Hui, et al.
Publicado: (2016)

IL-27-Induced Gene Expression Is Downregulated in HIV-Infected Subjects
por: Guzzo, Christina, et al.
Publicado: (2012)

Editorial: IL-27 in health and disease
por: Imamichi, Tomozumi, et al.
Publicado: (2023)

Capturing Complex Vaccine-Immune-Disease Relationships for Free-Ranging Koalas: Higher Chlamydial Loads Are Associated With Less IL17 Expression and More Chlamydial Disease
por: Lizárraga, David, et al.
Publicado: (2020)

IL-27, IL-30, and IL-35: A Cytokine Triumvirate in Cancer
por: Kourko, Olena, et al.
Publicado: (2019)

Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1β production by DCs
por: Arae, Ken, et al.
Publicado: (2018)

IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation
por: Dong, Zhaoxing, et al.
Publicado: (2015)

Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27
por: Xu, Mingli, et al.
Publicado: (2010)

Decreased IL-27 Negatively Correlated with Th17 Cells in Non-Small-Cell Lung Cancer Patients
por: Duan, Minchao, et al.
Publicado: (2015)

NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs
por: Schleicher, Ulrike, et al.
Publicado: (2007)

Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection
por: Klatt, Nichole R., et al.
Publicado: (2012)

Downregulation of macrophage IL-12 production by tumor-derived IL-11
por: Torroella, M, et al.
Publicado: (2001)

Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes
por: Petes, Carlene, et al.
Publicado: (2018)

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
por: Choi, Yeon Ho, et al.
Publicado: (2019)

IL-27/IL-27RA signaling may modulate inflammation and progression of benign prostatic hyperplasia via suppressing the LPS/TLR4 pathway
por: Lo, Hua-Cheng, et al.
Publicado: (2020)

Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control
por: Ruiz-Riol, M., et al.
Publicado: (2017)

IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells
por: Wittmann, Miriam, et al.
Publicado: (2012)

IL-23/IL-27 Ratio in Peripheral Blood of Patients with Breast Cancer
por: Khodadadi, Ali, et al.
Publicado: (2014)

IL-27 Counteracts Neuropathic Pain Development Through Induction of IL-10
por: Fonseca, Miriam M., et al.
Publicado: (2020)

Decreased serum levels of IL-27and IL-35 in patients with Graves disease
por: Saeed, Malek-Hosseini, et al.
Publicado: (2020)

IL-17, IL-27, and IL-33: A Novel Axis Linked to Immunological Dysfunction During Sepsis
por: Morrow, Kristen N., et al.
Publicado: (2019)

Correction to: IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
por: Choi, Yeon Ho, et al.
Publicado: (2019)

Chlamydial Lung Infection Induces Transient IL-9 Production Which Is Redundant for Host Defense against Primary Infection
por: Peng, Ying, et al.
Publicado: (2015)

IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages
por: Jung, Joo-Yong, et al.
Publicado: (2014)

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression
por: Casella, Giacomo, et al.
Publicado: (2017)

IL-27 Regulated CD4(+)IL-10(+) T Cells in Experimental Sjögren Syndrome
por: Qi, Jingjing, et al.
Publicado: (2020)

IL-30(†) (IL-27A): a familiar stranger in immunity, inflammation, and cancer
por: Min, Booki, et al.
Publicado: (2021)

Predicting roles of IL-27 and IL-32 in determining the severity and outcome of COVID-19
por: Zamani, Batool, et al.
Publicado: (2022)

IL-27, targeting antigen presenting cells, promotes Th17 differentiation and colitis in mice
por: Visperas, Anabelle, et al.
Publicado: (2013)

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection
por: Montes de Oca, Marcela, et al.
Publicado: (2020)

Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection
por: Li, Jing, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6hhd756b3tkphead0na8id3f2v