The Mechanism of Action of SAAP-148 Antimicrobial Peptide as Studied with NMR and Molecular Dynamics Simulations

Background: SAAP-148 is an antimicrobial peptide derived from LL-37. It exhibits excellent activity against drug-resistant bacteria and biofilms while resisting degradation in physiological conditions. Despite its optimal pharmacological properties, its mechanism of action at the molecular level has...

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Detalles Bibliográficos
Autores principales: Adélaïde, Morgane, Salnikov, Evgeniy, Ramos-Martín, Francisco, Aisenbrey, Christopher, Sarazin, Catherine, Bechinger, Burkhard, D’Amelio, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051583/
https://www.ncbi.nlm.nih.gov/pubmed/36986623
http://dx.doi.org/10.3390/pharmaceutics15030761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051583/
https://www.ncbi.nlm.nih.gov/pubmed/36986623
http://dx.doi.org/10.3390/pharmaceutics15030761

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