Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs

The purpose of this study was to investigate the applicability of the Gastrointestinal Simulator (GIS), a multi-compartmental dissolution model, to predict the in vivo performance of Biopharmaceutics Classification System (BCS) Class IIa compounds. As the bioavailability enhancement of poorly solubl...

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Detalles Bibliográficos
Autores principales: Katona, Miklós Tamás, Nagy-Katona, Lili, Szabó, Réka, Borbás, Enikő, Tonka-Nagy, Péter, Takács-Novák, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051608/
https://www.ncbi.nlm.nih.gov/pubmed/36986614
http://dx.doi.org/10.3390/pharmaceutics15030753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051608/
https://www.ncbi.nlm.nih.gov/pubmed/36986614
http://dx.doi.org/10.3390/pharmaceutics15030753

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