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Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons

Kaurenoic acid (KA) is a diterpene extracted from Sphagneticola trilobata (L.) Pruski. KA presents analgesic properties. However, the analgesic activity and mechanisms of action of KA in neuropathic pain have not been investigated so far; thus, we addressed these points in the present study. A mouse...

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Detalles Bibliográficos
Autores principales: Zaninelli, Tiago H., Mizokami, Sandra S., Bertozzi, Mariana M., Saraiva-Santos, Telma, Pinho-Ribeiro, Felipe A., de Oliveira, Gabriele Inácio, Streck, Renata, Araújo, Eduardo J. A., Arakawa, Nilton S., Borghi, Sergio M., Casagrande, Rubia, Verri, Waldiceu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051686/
https://www.ncbi.nlm.nih.gov/pubmed/36986443
http://dx.doi.org/10.3390/ph16030343