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Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons
Kaurenoic acid (KA) is a diterpene extracted from Sphagneticola trilobata (L.) Pruski. KA presents analgesic properties. However, the analgesic activity and mechanisms of action of KA in neuropathic pain have not been investigated so far; thus, we addressed these points in the present study. A mouse...
Autores principales: | Zaninelli, Tiago H., Mizokami, Sandra S., Bertozzi, Mariana M., Saraiva-Santos, Telma, Pinho-Ribeiro, Felipe A., de Oliveira, Gabriele Inácio, Streck, Renata, Araújo, Eduardo J. A., Arakawa, Nilton S., Borghi, Sergio M., Casagrande, Rubia, Verri, Waldiceu A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051686/ https://www.ncbi.nlm.nih.gov/pubmed/36986443 http://dx.doi.org/10.3390/ph16030343 |
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