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SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum

The golden Syrian hamster (Mesocricetus auratus) is now commonly used in preclinical research for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the assessment of vaccines, drugs and therapeutics. Here, we show that hamsters inoculated via the intranasal rout...

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Detalles Bibliográficos
Autores principales: Handley, Alastair, Ryan, Kathryn A., Davies, Elizabeth R., Bewley, Kevin R., Carnell, Oliver T., Challis, Amy, Coombes, Naomi S., Fotheringham, Susan A., Gooch, Karen E., Charlton, Michael, Harris, Debbie J., Kennard, Chelsea, Ngabo, Didier, Weldon, Thomas M., Salguero, Francisco J., Funnell, Simon G. P., Hall, Yper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051760/
https://www.ncbi.nlm.nih.gov/pubmed/36992457
http://dx.doi.org/10.3390/v15030748