Cargando…

SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum

The golden Syrian hamster (Mesocricetus auratus) is now commonly used in preclinical research for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the assessment of vaccines, drugs and therapeutics. Here, we show that hamsters inoculated via the intranasal rout...

Descripción completa

Detalles Bibliográficos
Autores principales:	Handley, Alastair, Ryan, Kathryn A., Davies, Elizabeth R., Bewley, Kevin R., Carnell, Oliver T., Challis, Amy, Coombes, Naomi S., Fotheringham, Susan A., Gooch, Karen E., Charlton, Michael, Harris, Debbie J., Kennard, Chelsea, Ngabo, Didier, Weldon, Thomas M., Salguero, Francisco J., Funnell, Simon G. P., Hall, Yper
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051760/ https://www.ncbi.nlm.nih.gov/pubmed/36992457 http://dx.doi.org/10.3390/v15030748

Ejemplares similares

The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
por: Davies, Elizabeth R., et al.
Publicado: (2023)

Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
por: Ryan, Kathryn A., et al.
Publicado: (2023)

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19
por: Huo, Jiandong, et al.
Publicado: (2021)

Generation of transgenic golden Syrian hamsters
por: Gao, Mingming, et al.
Publicado: (2014)

Golden Syrian Hamster Models for Cancer Research
por: Wang, Zhongde, et al.
Publicado: (2022)

Development of a Hamster Natural Transmission Model of SARS-CoV-2 Infection
por: Dowall, Stuart, et al.
Publicado: (2021)

Infection with Seasonal H1N1 Influenza Results in Comparable Disease Kinetics and Host Immune Responses in Ferrets and Golden Syrian Hamsters
por: Paterson, Jemma, et al.
Publicado: (2023)

Comparative pathology of VIC01 isolate and Omicron variant of SARS-CoV-2 infection, including a rechallenge model, in the Golden Syrian hamster
por: Rayner, E., et al.
Publicado: (2023)

Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters
por: Gallardo-Toledo, Eduardo, et al.
Publicado: (2023)

The production of skin lesions and lymphocytic leukemia in the Syrian (golden) hamster.
por: Fortner, J. G.
Publicado: (1965)

Rift Valley Fever Virus Infection in Golden Syrian Hamsters
por: Scharton, Dionna, et al.
Publicado: (2015)

An immunosuppressed Syrian golden hamster model for SARS-CoV infection
por: Schaecher, Scott R., et al.
Publicado: (2008)

Phytosterols protect against diet-induced hypertriglyceridemia in Syrian golden hamsters
por: Rideout, Todd C, et al.
Publicado: (2014)

Experimental Models in Syrian Golden Hamster Replicate Human Acute Pancreatitis
por: Wang, Yunan, et al.
Publicado: (2016)

Pathogenesis and transmission of SARS-CoV-2 in golden Syrian hamsters
por: Sia, Sin Fun, et al.
Publicado: (2020)

Full-Lung Prophylaxis against SARS-CoV-2 by One-Shot or Booster Intranasal Lentiviral Vaccination in Syrian Golden Hamsters
por: Vesin, Benjamin, et al.
Publicado: (2022)

RELATION OF CERTAIN ENDOCRINE DISTURBANCES TO SUSCEPTIBILITY OF GOLDEN SYRIAN HAMSTER TO EXPERIMENTAL POLIOMYELITIS
por: Teodoru, Constantin V., et al.
Publicado: (1954)

Chronic effects of dietary exposure to amosite and chrysotile asbestos in Syrian golden hamsters.
por: McConnell, E E, et al.
Publicado: (1983)

Validation of assays to monitor immune responses in the Syrian golden hamster (Mesocricetus auratus)
por: Zivcec, Marko, et al.
Publicado: (2011)

Efficient Gene Targeting in Golden Syrian Hamsters by the CRISPR/Cas9 System
por: Fan, Zhiqiang, et al.
Publicado: (2014)

Corrigendum: Experimental Models in Syrian Golden Hamster Replicate Human Acute Pancreatitis
por: Wang, Yunan, et al.
Publicado: (2016)

Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus
por: Safronetz, David, et al.
Publicado: (2011)

Depletion of Alveolar Macrophages Does Not Prevent Hantavirus Disease Pathogenesis in Golden Syrian Hamsters
por: Hammerbeck, Christopher D., et al.
Publicado: (2016)

Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters
por: Westover, Jonna B., et al.
Publicado: (2018)

The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future
por: Hirose, Michiko, et al.
Publicado: (2018)

A novel cancer syndrome caused by KCNQ1-deficiency in the golden Syrian hamster
por: Li, Rong, et al.
Publicado: (2018)

Using a Syrian (Golden) Hamster Biological Model for the Evaluation of Recombinant Anthrax Vaccines
por: Kravchenko, Tatiana, et al.
Publicado: (2021)

Distribution and photodynamic effect of disulphonated aluminium phthalocyanine in the pancreas and adjacent tissues in the Syrian golden hamster.
por: Nuutinen, P. J., et al.
Publicado: (1991)

The Effect of Concomitant Ethanol and Opium Consumption on Lipid Profiles and Atherosclerosis in Golden Syrian Hamster’s Aorta
por: Shahryari, Jahanbanoo, et al.
Publicado: (2013)

Antihyperlipidemic and Antioxidant Effects of C-phycocyanin in Golden Syrian Hamsters Fed with a Hypercholesterolemic Diet
por: Sheu, Ming-Jyh, et al.
Publicado: (2013)

Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters
por: Zhang, Shaojie, et al.
Publicado: (2014)

The Metabolic Changes of Artesunate and Ursolic Acid on Syrian Golden Hamsters Fed with the High-Fat Diet
por: Pu, Shichen, et al.
Publicado: (2020)

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
por: Qiao, Wei, et al.
Publicado: (2022)

Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2
por: Becker, Kathrin, et al.
Publicado: (2021)

Severe Acute Respiratory Syndrome Coronavirus 2 Vasculopathy in a Syrian Golden Hamster Model
por: Ball, Erin E., et al.
Publicado: (2023)

Establishment of a Nipah Virus Disease Model in Hamsters, including a Comparison of Intranasal and Intraperitoneal Routes of Challenge
por: Findlay-Wilson, Stephen, et al.
Publicado: (2023)

Selectivity of the photosensitiser Tookad® for photodynamic therapy evaluated in the Syrian golden hamster cheek pouch tumour model
por: Borle, F, et al.
Publicado: (2003)

Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster.
por: Mlkvy, P., et al.
Publicado: (1996)

Nasal Associated Lymphoid Tissue of the Syrian Golden Hamster Expresses High Levels of PrP(C)
por: Clouse, Melissa D., et al.
Publicado: (2015)

EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS
por: Manimaran, Asokan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a2s1pk9q7054co392sosmppo26