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Thermosensitive Polymer-Modified Mesoporous Silica for pH and Temperature-Responsive Drug Delivery

A mesoporous silica-based drug delivery system (MS@PNIPAm-PAAm NPs) was synthesized by conjugating the PNIPAm-PAAm copolymer onto the mesoporous silica (MS) surface as a gatekeeper that responds to temperature and pH changes. The drug delivery studies are carried out in vitro at different pH (7.4, 6...

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Detalles Bibliográficos
Autores principales: Thirupathi, Kokila, Santhamoorthy, Madhappan, Radhakrishnan, Sivaprakasam, Ulagesan, Selvakumari, Nam, Taek-Jeong, Phan, Thi Tuong Vy, Kim, Seong-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051764/
https://www.ncbi.nlm.nih.gov/pubmed/36986656
http://dx.doi.org/10.3390/pharmaceutics15030795