Synergy between Membrane Currents Prevents Severe Bradycardia in Mouse Sinoatrial Node Tissue

Bradycardia is initiated by the sinoatrial node (SAN), which is regulated by a coupled-clock system. Due to the clock coupling, reduction in the ‘funny’ current (I(f)), which affects SAN automaticity, can be compensated, thus preventing severe bradycardia. We hypothesize that this fail-safe system i...

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Detalles Bibliográficos
Autores principales: Arbel Ganon, Limor, Davoodi, Moran, Alexandrovich, Alexandra, Yaniv, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051777/
https://www.ncbi.nlm.nih.gov/pubmed/36982861
http://dx.doi.org/10.3390/ijms24065786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051777/
https://www.ncbi.nlm.nih.gov/pubmed/36982861
http://dx.doi.org/10.3390/ijms24065786

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