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Synergy between Membrane Currents Prevents Severe Bradycardia in Mouse Sinoatrial Node Tissue
Bradycardia is initiated by the sinoatrial node (SAN), which is regulated by a coupled-clock system. Due to the clock coupling, reduction in the ‘funny’ current (I(f)), which affects SAN automaticity, can be compensated, thus preventing severe bradycardia. We hypothesize that this fail-safe system i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051777/ https://www.ncbi.nlm.nih.gov/pubmed/36982861 http://dx.doi.org/10.3390/ijms24065786 |