Impaired Autophagy in Krabbe Disease: The Role of BCL2 and Beclin-1 Phosphorylation

Autophagic impairment was identified in many lysosomal storage diseases and adult neurodegenerative diseases. It seems that this defect could be directly related to the appearance of a neurodegenerative phenotype and could contribute to worsen metabolite accumulation and lysosomal distress. Thus, au...

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Detalles Bibliográficos
Autores principales: Papini, Nadia, Todisco, Roberta, Giussani, Paola, Dei Cas, Michele, Paroni, Rita, Giallanza, Chiara, Tringali, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051825/
https://www.ncbi.nlm.nih.gov/pubmed/36983059
http://dx.doi.org/10.3390/ijms24065984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051825/
https://www.ncbi.nlm.nih.gov/pubmed/36983059
http://dx.doi.org/10.3390/ijms24065984

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