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Impaired Autophagy in Krabbe Disease: The Role of BCL2 and Beclin-1 Phosphorylation
Autophagic impairment was identified in many lysosomal storage diseases and adult neurodegenerative diseases. It seems that this defect could be directly related to the appearance of a neurodegenerative phenotype and could contribute to worsen metabolite accumulation and lysosomal distress. Thus, au...
Autores principales: | Papini, Nadia, Todisco, Roberta, Giussani, Paola, Dei Cas, Michele, Paroni, Rita, Giallanza, Chiara, Tringali, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051825/ https://www.ncbi.nlm.nih.gov/pubmed/36983059 http://dx.doi.org/10.3390/ijms24065984 |
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