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Open Reading Frame 4 Is Not Essential in the Replication and Infection of Genotype 1 Hepatitis E Virus

Genotype 1 hepatitis E virus (HEV-1), unlike other genotypes of HEV, has a unique small open reading frame known as ORF4 whose function is not yet known. ORF4 is located in an out-framed manner in the middle of ORF1, which encodes putative 90 to 158 amino acids depending on the strains. To explore t...

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Detalles Bibliográficos
Autores principales: Bai, Huimin, Ami, Yasushi, Suzaki, Yuriko, Doan, Yen Hai, Muramatsu, Masamichi, Li, Tian-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052008/
https://www.ncbi.nlm.nih.gov/pubmed/36992492
http://dx.doi.org/10.3390/v15030784