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Clinical and Mechanistic Implications of R-Loops in Human Leukemias
Genetic mutations or environmental agents are major contributors to leukemia and are associated with genomic instability. R-loops are three-stranded nucleic acid structures consisting of an RNA–DNA hybrid and a non-template single-stranded DNA. These structures regulate various cellular processes, i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052022/ https://www.ncbi.nlm.nih.gov/pubmed/36983041 http://dx.doi.org/10.3390/ijms24065966 |