Preparation and Characterization of Amorphous Solid Dispersions for the Solubilization of Fenretinide

Fenretinide (4-HPR), a retinoid derivative, has shown high antitumor activity, a low toxicological profile, and no induction of resistance. Despite these favorable features, the variability in oral absorption due to its low solubility combined with the high hepatic first pass effect strongly reduce...

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Detalles Bibliográficos
Autores principales: Zuccari, Guendalina, Russo, Eleonora, Villa, Carla, Zorzoli, Alessia, Marimpietri, Danilo, Marchitto, Leonardo, Alfei, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052200/
https://www.ncbi.nlm.nih.gov/pubmed/36986487
http://dx.doi.org/10.3390/ph16030388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052200/
https://www.ncbi.nlm.nih.gov/pubmed/36986487
http://dx.doi.org/10.3390/ph16030388

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