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Transfer learning identifies sequence determinants of cell-type specific regulatory element accessibility
Dysfunction of regulatory elements through genetic variants is a central mechanism in the pathogenesis of disease. To better understand disease etiology, there is consequently a need to understand how DNA encodes regulatory activity. Deep learning methods show great promise for modeling of biomolecu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052367/ https://www.ncbi.nlm.nih.gov/pubmed/37007588 http://dx.doi.org/10.1093/nargab/lqad026 |