Identification and in vitro functional assessment of 10 CYP2C9 variants found in Chinese Han subjects

Cytochrome P450 2C9 (CYP2C9) participates in about 15% of clinical drug metabolism, and its polymorphism is associated with individual drug metabolism differences, which may lead to the adverse drug reactions (ADRs). In this study, 1163 Chinese Han individuals were recruited to investigate their dis...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Qi, Yuying, Wang, Shuanghu, Zhao, Fangling, Zou, Lili, Zhou, Quan, Geng, Peiwu, Hong, Yun, Yang, Hang, Luo, Qingfeng, Cai, Jianping, Wu, Hualan, Wang, Dongxu, Chen, Hao, Yang, Jiefu, Dai, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052410/
https://www.ncbi.nlm.nih.gov/pubmed/37008923
http://dx.doi.org/10.3389/fendo.2023.1139805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052410/
https://www.ncbi.nlm.nih.gov/pubmed/37008923
http://dx.doi.org/10.3389/fendo.2023.1139805

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