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Identification and in vitro functional assessment of 10 CYP2C9 variants found in Chinese Han subjects
Cytochrome P450 2C9 (CYP2C9) participates in about 15% of clinical drug metabolism, and its polymorphism is associated with individual drug metabolism differences, which may lead to the adverse drug reactions (ADRs). In this study, 1163 Chinese Han individuals were recruited to investigate their dis...
Autores principales: | Zhang, Qing, Qi, Yuying, Wang, Shuanghu, Zhao, Fangling, Zou, Lili, Zhou, Quan, Geng, Peiwu, Hong, Yun, Yang, Hang, Luo, Qingfeng, Cai, Jianping, Wu, Hualan, Wang, Dongxu, Chen, Hao, Yang, Jiefu, Dai, Dapeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052410/ https://www.ncbi.nlm.nih.gov/pubmed/37008923 http://dx.doi.org/10.3389/fendo.2023.1139805 |
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