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Recombinant irisin prevents cell death and mineralization defects induced by random positioning machine exposure in primary cultures of human osteoblasts: A promising strategy for the osteoporosis treatment

Spaceflight exposure, like prolonged skeletal unloading, is known to result in significant bone loss, but the molecular mechanisms responsible are still partly unknown. This impairment, characterizing both conditions, suggests the possibility of identifying common signalling pathways and developing...

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Detalles Bibliográficos
Autores principales: Cariati, Ida, Bonanni, Roberto, Rinaldi, Anna Maria, Marini, Mario, Iundusi, Riccardo, Gasbarra, Elena, Tancredi, Virginia, Tarantino, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052411/
https://www.ncbi.nlm.nih.gov/pubmed/37008023
http://dx.doi.org/10.3389/fphys.2023.1107933