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Modulatory Role of Autophagy in Metformin Therapeutic Activity toward Doxorubicin-Induced Nephrotoxicity

Doxorubicin (DOX) is a frequent chemotherapeutic drug used to treat various malignant tumors. One of the key factors that diminish its therapeutic importance is DOX-induced nephrotoxicity. The first-line oral antidiabetic drug is metformin (Met), which also has antioxidant properties. The purpose of...

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Detalles Bibliográficos
Autores principales: Antar, Samar A., Abd-Elsalam, Marwa, Abdo, Walied, Abdeen, Ahmed, Abdo, Mohamed, Fericean, Liana, Raslan, Nahed A., Ibrahim, Samah F., Sharif, Asmaa F., Elalfy, Amira, Nasr, Hend E., Zaid, Ahmed B., Atia, Rania, Atwa, Ahmed M., Gebba, Mohammed A., Alzokaky, Amany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052439/
https://www.ncbi.nlm.nih.gov/pubmed/36977038
http://dx.doi.org/10.3390/toxics11030273