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DOPE/CHEMS-Based EGFR-Targeted Immunoliposomes for Docetaxel Delivery: Formulation Development, Physicochemical Characterization and Biological Evaluation on Prostate Cancer Cells

Docetaxel (DTX) is a non-selective antineoplastic agent with low solubility and a series of side effects. The technology of pH-sensitive and anti-epidermal growth factor receptor (anti-EGFR) immunoliposomes aims to increase the selective delivery of the drug in the acidic tumor environment to cells...

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Detalles Bibliográficos
Autores principales: Moreira, Thais da Silva, Silva, Alan Denis Olivindo, Vasconcelos, Bianca Rodrigues Farias, Santos, Elias da Silva, de Sousa, Ana Carolina Cruz, de Freitas, João Vito Barroso, de Oliveira, Yara Santiago, Vidal, Laura Maria Teodorio, Ribeiro, Fábio de Oliveira Silva, de Araújo, Alyne Rodrigues, Vieira Neto, José de Brito, Pessoa, Cláudia do Ó, Petrilli, Raquel, Eloy, Josimar O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052572/
https://www.ncbi.nlm.nih.gov/pubmed/36986777
http://dx.doi.org/10.3390/pharmaceutics15030915