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One-Pot Radiosynthesis of [(18)F]Anle138b—5-(3-Bromophenyl)-3-(6-[(18)F]fluorobenzo[d][1,3]dioxol-5-yl)-1H-pyrazole—A Potential PET Radiotracer Targeting α-Synuclein Aggregates
Availability of PET imaging radiotracers targeting α-synuclein aggregates is important for early diagnosis of Parkinson’s disease and related α-synucleinopathies, as well as for the development of new therapeutics. Derived from a pyrazole backbone, (11)C-labelled derivatives of anle138b (3-(1,3-benz...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052605/ https://www.ncbi.nlm.nih.gov/pubmed/36985703 http://dx.doi.org/10.3390/molecules28062732 |