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One-Pot Radiosynthesis of [(18)F]Anle138b—5-(3-Bromophenyl)-3-(6-[(18)F]fluorobenzo[d][1,3]dioxol-5-yl)-1H-pyrazole—A Potential PET Radiotracer Targeting α-Synuclein Aggregates

Availability of PET imaging radiotracers targeting α-synuclein aggregates is important for early diagnosis of Parkinson’s disease and related α-synucleinopathies, as well as for the development of new therapeutics. Derived from a pyrazole backbone, (11)C-labelled derivatives of anle138b (3-(1,3-benz...

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Detalles Bibliográficos
Autores principales: Orlovskaya, Viktoriya V., Fedorova, Olga S., Viktorov, Nikolai B., Vaulina, Daria D., Krasikova, Raisa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052605/
https://www.ncbi.nlm.nih.gov/pubmed/36985703
http://dx.doi.org/10.3390/molecules28062732