A Polysaccharide-RBD-Fc-Conjugated COVID-19 Vaccine, SCTV01A, Showed High Immunogenicity and Low Toxicity in Animal Models

We previously developed a polysaccharide-–RBD-conjugated nanoparticle vaccine which induced protective efficacy against SARS-CoV-2 in a mouse model. Here, we newly developed a vaccine, SCTV01A, by chemically conjugating recombinant SARS-CoV-2 RBD-Fc and PPS14 (Streptococcus pneumoniae serotype type...

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Detalles Bibliográficos
Autores principales: Sun, Chunyun, Kong, Desheng, Guo, Erhong, Zhao, Jun, Jia, Jilei, Wang, Rui, Ma, Juan, Chen, Meng, Lu, Jianbo, Yu, Chulin, Li, Kuokuo, Xie, Liangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052645/
https://www.ncbi.nlm.nih.gov/pubmed/36992109
http://dx.doi.org/10.3390/vaccines11030526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052645/
https://www.ncbi.nlm.nih.gov/pubmed/36992109
http://dx.doi.org/10.3390/vaccines11030526

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