p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer

BACKGROUND: During cell apoptosis, the C-terminus of BAP31 is cleaved by caspase-8 and generates p20BAP31, which has been shown to induce an apoptotic pathway between the endoplasmic reticulum (ER) and mitochondria. However, the underlying mechanisms of p20BAP31 in cell apoptosis remains unclear. ME...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaohan, Li, Guoxun, Zhu, Benzhi, Zang, Jingnan, Lan, Tian, Jiang, Rui, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052827/
https://www.ncbi.nlm.nih.gov/pubmed/36977989
http://dx.doi.org/10.1186/s11658-023-00434-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052827/
https://www.ncbi.nlm.nih.gov/pubmed/36977989
http://dx.doi.org/10.1186/s11658-023-00434-z

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