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BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes

Epigenetic modifications of histones are associated with development and pathogenesis of disease. Existing approaches cannot provide insights into long-range interactions and represent the average chromatin state. Here we describe BIND&MODIFY, a method using long-read sequencing for profiling hi...

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Detalles Bibliográficos
Autores principales: Weng, Zhe, Ruan, Fengying, Chen, Weitian, Chen, Zhichao, Xie, Yeming, Luo, Meng, Xie, Zhe, Zhang, Chen, Wang, Juan, Sun, Yuxin, Fang, Yitong, Guo, Mei, Tan, Chen, Chen, Wenfang, Tong, Yiqin, Li, Yaning, Wang, Hongqi, Tang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052867/
https://www.ncbi.nlm.nih.gov/pubmed/36991510
http://dx.doi.org/10.1186/s13059-023-02896-y