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BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes
Epigenetic modifications of histones are associated with development and pathogenesis of disease. Existing approaches cannot provide insights into long-range interactions and represent the average chromatin state. Here we describe BIND&MODIFY, a method using long-read sequencing for profiling hi...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052867/ https://www.ncbi.nlm.nih.gov/pubmed/36991510 http://dx.doi.org/10.1186/s13059-023-02896-y |