Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation

The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) approach was employed to optimize DTB-loaded nano-emulgel using a central composite design (CCD). Emulgel was prepared using th...

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Detalles Bibliográficos
Autores principales: Donthi, Mahipal Reddy, Saha, Ranendra Narayan, Singhvi, Gautam, Dubey, Sunil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052882/
https://www.ncbi.nlm.nih.gov/pubmed/36986597
http://dx.doi.org/10.3390/pharmaceutics15030736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052882/
https://www.ncbi.nlm.nih.gov/pubmed/36986597
http://dx.doi.org/10.3390/pharmaceutics15030736

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