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Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation

The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) approach was employed to optimize DTB-loaded nano-emulgel using a central composite design (CCD). Emulgel was prepared using th...

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Detalles Bibliográficos
Autores principales:	Donthi, Mahipal Reddy, Saha, Ranendra Narayan, Singhvi, Gautam, Dubey, Sunil Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052882/ https://www.ncbi.nlm.nih.gov/pubmed/36986597 http://dx.doi.org/10.3390/pharmaceutics15030736

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