α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes

In this study, α-ω-disubstituted polyamines exhibit a range of potentially useful biological activities, including antimicrobial and antibiotic potentiation properties. We have prepared an expanded set of diarylbis(thioureido)polyamines that vary in central polyamine core length, identifying analogu...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Dan, Cadelis, Melissa M., Rouvier, Florent, Troia, Thomas, Edmeades, Liam R., Fraser, Kyle, Gill, Evangelene S., Bourguet-Kondracki, Marie-Lise, Brunel, Jean Michel, Copp, Brent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052977/
https://www.ncbi.nlm.nih.gov/pubmed/36982955
http://dx.doi.org/10.3390/ijms24065882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052977/
https://www.ncbi.nlm.nih.gov/pubmed/36982955
http://dx.doi.org/10.3390/ijms24065882

Ejemplares similares