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CHIR99021-Treated Osteocytes with Wnt Activation in 3D-Printed Module Form an Osteogenic Microenvironment for Enhanced Osteogenesis and Vasculogenesis

Finding a bone implant that has high bioactivity that can safely drive stem cell differentiation and simulate a real in vivo microenvironment is a challenge for bone tissue engineering. Osteocytes significantly regulate bone cell fate, and Wnt-activated osteocytes can reversely regulate bone formati...

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Detalles Bibliográficos
Autores principales: Luo, Yisheng, Liu, Yangxi, Wang, Bo, Tu, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052982/
https://www.ncbi.nlm.nih.gov/pubmed/36983081
http://dx.doi.org/10.3390/ijms24066008